Poor prognosis osteosarcoma: new therapeutic approach
نویسندگان
چکیده
منابع مشابه
Overexpression of EZH2 is associated with the poor prognosis in osteosarcoma and function analysis indicates a therapeutic potential
Osteosarcoma is a primary malignant bone tumor that has a poor prognosis due to local recurrence, metastasis, and chemotherapy resistance. Therefore, there is an urgent need to develop novel potential therapeutic targets for osteosarcoma. Enhancer of zeste homologue 2 (EZH2) is a member of the polycomb group of proteins, which has important functions in epigenetic silencing and cell cycle regul...
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ژورنال
عنوان ژورنال: Bone Marrow Transplantation
سال: 2008
ISSN: 0268-3369,1476-5365
DOI: 10.1038/bmt.2008.71